James S replied: "There a different medications for each delivery method. Nebulizers require a much larger amount of medication to have the same effect as an inhaler, as they are less efficient than inhalers. Inhalers are more convenient, portable, and easy to use at home by yourself. Nebulizers are usually not portable (but there are portable models), normally need to be plugged into a wall to run, require an air compressor or oxygen system to run, and take a lot longer than an inhaler to give yourself a treatment.
For example:
Albuterol/Salbutamol nebulizer solution is normally 2.5 mg and would usually take 6-10 minutes to give. You could get the same therapeutic effect with 2 inhalations from an inhaler of Albuterol/Salbutamol with a holding chamber. Administering your treatment from an inhaler would take about a minute.
Inhalers are faster, inexpensive, portable, and reasonably easy for a regular person to use with proper training. Neither with get you high if you are using the device correctly. If you leave your nebulizer on for "too long", you will not get high. I have given a lot of breathing treatments and nobody has gotten high from them ever.
For other respiratory medications, some are available as nebulizer solution and some as various kinds of inhalers. Some are in nebulizer and inhaler forms. It all depends on what drug it is.
For Albuterol/Salbutamol, normal doses are:
Nebulizer (generic): 2.5 mg
Metered Dose Inhaler (regular inhaler): 2 inhalations of 100 mcg [the only dose] inhaled Albuterol
Dry Powder Inhaler (like an Advair discus): 1 inhalation of Glaxo Smith Kline Ventolin discus, which is 200 mcg.
All three will work just as well as the other, in a perfect world. If you can't inhale in an co-ordinated manner, a nebulizer would work best. Otherwise, an inhaler of some form should be more useful and convenient."
Medications for Nebulizer Treatments - LIVESTRONG.COM
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