Caffeine Metabolize Information

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How does caffeine get metabolized in the body? Once caffeine is ingested, what does it break down into? Is there a chemical reaction formula for it? And how does it pass through the body?

mkpinjani replied: "Caffeine, an alkaloid (C8H10O2N4H2O) found in coffee, tea, cacao, and some other plants. It is also present in most cola beverages. Caffeine was discovered in coffee in 1820. In 1838 it was established that theine, discovered in tea in 1827, is identical to caffeine. The drug increases the blood pressure, stimulates the central nervous system, promotes urine formation, and stimulates the action of the heart and lungs. Caffeine is used in treating migraine because it constricts the dilated blood vessels and thereby reduces the pain. It also increases the potency of analgesics such as aspirin, and it can somewhat relieve asthma attacks by widening the bronchial airways. Caffeine is produced commercially chiefly as a by-product in making caffeine-free coffee. Caffeine has been suggested as a possible cause of cancer or of birth defects. No studies, however, have yet confirmed any of these charges. Persons who stop drinking coffee do sometimes experience withdrawal headaches. The U.S. Food and Drug Administration does not include caffeine on its generally recognized as safe (GRAS) list, but acknowledges no clear evidence of hazard at normal levels of use."

Can a person lose the ability to metabolize caffeine? I am a 48 year-old woman. I have noticed that over the past few years I have lost the ability to tolerate caffeine. Usually I don't have any, or very little caffeine (decaf coffee and tea, for instance). This is because, about 10 years ago, I was drinking a cup of strong "real" coffee every day and developed breast pain from it. The specialist I saw said it was a common benign condition (nothing to worry about) that was being made worse by the caffeine. Sure enough, when I cut out the caffeine the breast pain went away within one month. Nowadays, if I have a cup of regular coffee, or an Excedrin with caffeine, I feel very ill for many hours. My heart pounds so hard, and I get so much anxiety that I feel like I'm going to have a panic attack or pass out. The feeling can last for hours if I accidentally drink something with a lot of caffeine. It also seems to affect my digestion, giving me reflux symptoms for days afterward. The only medication I take is Synthroid for my Hypothyroidism and an oral contraceptive (same one I've been taking for the past several years). The last time I got my TSH checked it was 1.0, which is where the doctor wants it, and where it has been for many years. I know that having a TSH so close to the "Hyperthyroid" range can make a person feel jumpy, but my reaction to caffeine in the past few months has been getting worse for no apparent reason. Anyway, has this happened to anyone else, and if so did you find out the reason behind it?

Isles8920 replied: "I've been searching for someone who's gone through the same exact thing as I... couple years ago, I developed the same symptoms because I was abusing ( if you can call it that) coffee/ caffeine...at first it was really bad, couldn't get off the couch, felt like i was getting panic attacks, nauseous , moody... it got better over the months, I started to exercise and try to eat better which helped some what.. i went to the doctor, they took a blood test .. couldn't determine anything significant ( said it could be anxiety but i know for a fact it isn't)...by the way, i've stopped my intake of sugar and caffeine of course because i just cant handle it especially caffeine..nowadays I can go weeks feeling just fine as long as I stay away from sugar or caffeine.. I hope you get an answer soon because i have also been looking for o"

how much caffeine does it take to become addicted?might my current headache be related to caffeine withdrawal? what is the equivilent of this in number of coffees. Also, how is caffeine metabolized, how long does it stay in the system, how long after your last caffeine intake before you experience withdrawal symptoms, and how long do you need to abstain from caffeine before you are no longer addicted. I'm just curious, in the last 2or 3 days I have been drinking energy drinks, this morning I had a coffee, and this evening I have a headache. I don't normally drink coffee or energy drinks. Might I be addicted already and suffering withdrawal or is my headache something completely different? Any references to comprehensive websites appreciated.

frgyjo replied: "You may just be dehydrated from the intake of caffeine and sugar. If you are suffering from caffeine withdrawl the headache would be accompanied by a shaky almost nervous feeling or difficulty concentrating."

Will caffeine raise your alcohol tolerance? I read this on Wikipedia while looking up the drug that I consume 280-1000mg daily (either a single Cocaine Energy Drink or many energy drinks daily, it depends on what day of the week it is and what commitments I have). Mind you, I do not consume caffeine for the way drinking an energy drink every day looks. I simply enjoy it. I am young and realize the risks, but understand the drug and I am asking this question to understand it more. I acknowledge that caffeine can cause heart attacks and other issues, but that is later in life, at my age it is easy to metabolize caffeine without health issues. Lastly, I know that caffeine is a diuretic, drink plenty of water, and sometimes take calcium supplements to keep from an imbalance. So my question related to this statement on Wikipedia: "Caffeine is metabolized in the liver by the cytochrome P450 oxidase enzyme system..." Does that mean that slowly raising my caffeine tolerance to a consistent 300-or-so-mg of caffeine per day raise my tolerance by strengthening my liver (technically weakening it, but I consistently consume caffeine that my tolerance is consistent). I also understand the difference between tolerance and still yet to be metabolized caffeine in my system, I know that caffeine has a half life of around 5 hours. So 300mg becomes 9.375mg after 25 hours. Anyway thanks for any help I get with this question!

Kiwi. replied: "Cocaine energy drink?!"

Jack Wills replied: "i drink a lot of caffeine every day too, but i have a very low tolerance to alcohol - im a total lightweight. alcohol tolerance is not affected by how much caffeine you drink. it is affected by your build, and how much alcohol you drink on a regular basis. regularly consuming alcohol is how to build up your tolerance to it. sorry but i dont think your plan will work, it hasnt worked for me."

Cocaine help metabolize alcohol faster? Now supposedly if you drink coffee, cause of the caffeine, it helps sober you up because the caffeine helps to speed up your metabolism. I was just wondering, since cocaine is a much more powerful stimulant if that would help metabolize it faster. not just make you feel less drunk, but actually spped up the process. And PLEASE no answers about how i shoouldn't be doing cocaine & what not...it is a legitimate question.

rannico10 replied: "from my experience i can tell that cocaine doesn t speed up the process of metab. alcohol it just neutralize it for the time you are taking cocaine.... it is also very dangerous drinking a and taking cocaine because its effect multiply when used with alcohol."

rjohnson442000 replied: "Sorry the answer is nope. Your liver can only work at one rate."

Caffeine + Tylenol? Okay, tonight I was planning on a good old fashioned halo bender. I consumed about 750 mg of caffeine and out of nowhere I get called in for work the next day. There was no way I was going to fall asleep so I hit up the medicine cabinet and took 6 Tylenol cause they make me drowsy. I took six cause I'm a big guy. About ten minutes ago I find that they are extra strength. I seriously feel like a complete idiot asking this. Am I screwed? I take anti depressants as well. That's a lot for the liver to metabolize. I also gagged myself til my stomach was empty, but can 3 grams kill a 200 pound man?

max r replied: "your screwed"

Brandi replied: "No I am pretty sure you will be fine. You should however, drink some milk to help soothe your throat tissues. The acids from your stomach are very harsh and inducing vomiting is an awful thing to do to your throat. Try drinking a hot cup of Sleepy Time tea. It has soothing herbs in it to help you relax and fall asleep. As for the medication issue, if you are really concerned about the combo call poison control (listed in the front of your phone book where the emerg numbs are) and tell them what you have consumed and what you did to try to remedy the problem. You will feel stupid telling them too, but they aren't ever gonna meet you, so no big deal. They will let you know what you should do from there. Be sure you tell them about ALL meds taken in the past 24 hrs because some things do not pass thru your system as quickly as others. Good luck!"

Math help? OK heres my question... Robbie drinks 2 cups of soda each morning. Each cup contains 140 milligrams of caffeine. THe human body can metabolize about 12% of any caffeine remaining in the bloodstream each hour. To the nearest tenth, how may hours does it take until less than half the caffeine remains in Robbie's bloodstream? please solve and explain thank you

Dingus McCoy replied: "Where are you parents? Quit having everyone else do your homework"

peachie replied: "Here a couple of hints: How much total caffinee does he consume? If in the first hour the body takes care of 12%, how much is left after one hour?"

Bigferribunny replied: "After every hour, you have 88 percent of the caffeine in your bloodstream that you had the previous hour. You're looking to get to 50 percent of your original caffeine level. So you can set the equation up as follows: 0.88^t = 0.5 Where t is the number of hours. The 2 cups and 140 mg of caffeine are irrelevant. To solve, take the natural log of both sides: t*ln(0.88) = ln(0.5) t = ln(0.5)/(ln(0.88)) I don't have a calculator on me so I can't tell you what that number equals, but thats' how you solve it. Your friend, Bigferribunny"

E.G replied: "the total caffeine is 280 mg 12% of 280 is 33.6mg. if 33.6 mg takes 1 hour, lets find how long it takes for 140 mg(half of caffeine in his body) 33.6 : 140 = 1 : x 33.6 x = 140 x = 4.16 hours"

huskerchica replied: "I won't give you your answer, but all you have to do to solve it is to add 140mg and 140mg (for the two cups). Multiply the 280 times .12 (12%) to get how much is depleated after the first hour. Subtract that from 280mg and repeat until you get below 140mg."

Zach K replied: "You have 140MG of caffeine, you need to metabolize until you've got under 70MG, and if you metabolize -12% a hour, just take 140 and subtract 12%, you'll then have 123.2MG remaining after one hour. Subtract another 12% for the next hour, and you've got 108.4MG after two hours. Do that until you've got under 70MG, 7 hours."

mrgets replied: "Hello, We have 140 = 280 ( 1 - 12%)^t so .5 = .88^t now take the log of both sides and we have: log .5 = t* log(.88) divide both sides by log .88 giving us log.5/log.88 = t so t = 5.4 hours Hope this helps!!"

MAth geniuses!! pls help me!!? linh drinks 2 cups of coffee each morning. each cup contains 150 milgrams of caffine. the human body can metabolize about 11% of any caffeine remaining in the blood stream each hour. to the nearest tenth, how many hours does it take until less than half the caffeine remains in linh's bloodstream pls explain step by step! THANKS!!!

hurt replied: "next time to come to school. pay attention to your teacher. stop bothering the people around you. 2 x 150 = a a x 11% = b try to figure out the rest it's really easy"

Colin M replied: "This doesn't exactly take a math genius. 2 cups of coffee = 150 mg * 2 = 300 mg After 1 hour 300 mg * 11% = 267 mg After 2 hours 267 mg * 11% = 237.63 mg After 3 hours 237.63 * 11% = 211.49 mg After 4 hours 211.49 * 11% = 188.22 mg After 5 hours 188.22 * 11% = 167.52 mg After 6 hours 167.52 * 11% = 149.09 mg"

cactusjoe replied: "4.6 hours, 2 cups = 300 mg caffine x 11%=33 per hour 4.6 hours x 33= 151.8 mg - 300mg= leaves 148.2mg in blood stream, less than half"

copperhead replied: "This looked interesting! First you have to know how much caffine is in the bloodstream. 2 cups x 150 mg/cup = 300 mg In the first hour, the body metabolizes 11% (this is the same as 0.11) of the caffine. 300 mg x 0.11 = 33mg (this is the amount REMOVED from the bloodstream) How much is left after an hour? 300mg - 33mg = 267mg An hour later, another 11% is metabolized (and here's where it gets tricky). If 267mg was left at the end of hour 1, this is the number you have to work with. 267mg x 0.11 = 29.37mg (the amount removed in hour 2. How much is left in the bloodstream at the end of 2 hours? 267mg - 29.37mg = 237.63mg See how this is done? Keep working in this format till the amount at the end of the hour is less than 1/2 (150 mg) is left in the blood. Don't round off any numbers till you get below 150. You should be able to work this from here!"

daddyspanksalot replied: "The amount of caffine is irrelivant. 1.1% equals 6 minutes (one tenth of an hour) 50 /1.1% = 45.45 tenths of an hour or 4.6 hours until you have under 50% (rounded to the higher tenth to make it over 50% metabolized)."

Achintya s replied: "149.09 milligrams after 6 hours"

Bill F replied: "Daddyspan is wrong because there is less caffeine to metabolize each hour, yes the answer is 6 hours"

math help best answer given? A cup of coffee contains about 169 mg of caffeine and every hour approximately 16% of the amount of caffeine in the body is metabolized and eliminated. (a) Write C, the amount of caffeine in the body in mg as a function of t, the number of hours since the coffee was consumed. C(t)=

allen s replied: "C(t) = 169*(0.84^t)"

cregory replied: "at t=0 we have 169mg caffeine at t=1 we have (169)(.16) mg caffeine at t=2 we have 16% of what we had at t=1 or (.16){(169)(.16)}=(.16)(.16)(169) t=3 is going to be 16% of t=2 or (.16){(.16)(.16)(169)}=(.16)(.16)(.16)(169) and we can begin to see a pattern forming.at t= 3 it is (.16)^3 at t=2 , (.16)^2 down to t=0 where (.16)^0=1 so from this line of reasoning we can come up with a formula C(t)=169mg(.16)^t actually I'm wrong here I gave you formula for what was metabolized not what remains--same reasoning but it will be 1-.16=.84 left in body so C(t)=169mg(.84)^t sorry bout that"

ONE simple exponential function...am I right??? Ok, A typical cup of coffee contains about 100mg of caffeine and every hour appx. 16% of the amount of caffeine in the body is metabolized and eliminated a. Write C, the amount of caffeine in the body in mg as a function of t, the # of hours since time of consumption. I got C(t)=100(0.16)^t...if not PLEASE correct me!!! b. How much caffeine is in the body after 5 hours? Ok, first I 1. did 1-.16=.84 2. 100(0.84)=84 @ hour 1 By hour 5 I got 41.82 left...IS THIS CORRECT??? If not please correct me and explain how your answer is right and maybe (if u want) how I was wrong...just learned this today. THANKS!

T H replied: "41.82 mg is correct. But your C(t) is not. It should be 100(1-.16)^t=100(.84)^t. But you knew that. You did it right in the second part! :)"

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